Nyxus provided features

Pixel intensity features:


Nyxus feature code

Description

INTEGRATED_INTENSITY

Integrated intensity of the region of interest (ROI)

MEAN

Mean intensity value of the ROI

MEDIAN

The median value of pixels in the ROI

MIN

Minimum intensity value in the ROI

MAX

Maximum intensity value in the ROI

RANGE

Range between the maximmu and minimum

COVERED_IMAGE_INTENSITY_RANGE

intensity range of the ROI to intensity range of all the ROIs

STANDARD_DEVIATION

Standard deviation (unbiased)

STANDARD_DEVIATION_BIASED

Biased standard deviation

COV

Coefficient of variation

STANDARD_ERROR

Standard error

SKEWNESS

Skewness - the 3rd standardized moment

KURTOSIS

Kurtosis - the 4th standardized moment (Pearson formula)

EXCESS_KURTOSIS

Excess kurtosis - the 4th standardized moment (Fisher-corrected formula, IBSI feature IPH6)

HYPERSKEWNESS

Hyperskewness - the 5th standardized moment

HYPERFLATNESS

Hyperflatness - the 6th standardized moment

MEAN_ABSOLUTE_DEVIATION

Mean absolute deviation

MEDIAN_ABSOLUTE_DEVIATION

Median absolute deviation

ENERGY

ROI energy

ROOT_MEAN_SQUARED

Root of mean squared deviation

ENTROPY

ROI entropy - a measure of the amount of information (that is, randomness) in the ROI

MODE

The mode value of pixels in the ROI - the value that appears most often in a set of ROI intensity values

UNIFORMITY

Uniformity - measures how uniform the distribution of ROI intensities is

UNIFORMITY_PIU

Percent image uniformity, another measure of intensity distribution uniformity

P01, P10, P25, P75, P90, P99

1%, 10%, 25%, 75%, 90%, and 99% percentiles of intensity distribution

QCOD

quantile coefficient of dispersion

INTERQUARTILE_RANGE

Distribution’s interquartile range

ROBUST_MEAN_ABSOLUTE_DEVIATION

Robust mean absolute deviation

MASS_DISPLACEMENT

ROI mass displacement

Morphology features:


Nyxus feature code

Description

AREA_PIXELS_COUNT

ROI area in the number of pixels

AREA_UM2

ROI area in metric units

CENTROID_X

X-coordinate of the enter point of the ROI

CENTROID_Y

Y-coordinate of the center point of the ROI

COMPACTNESS

Mean squared distance of the object’s pixels from the centroid divided by the area. Compactness of a filled circle is 1, compactness of irregular objects or objects with holes is greater than 1

BBOX_YMIN

Y-position and size of the smallest axis-aligned box containing the ROI

BBOX_XMIN

X-position and size of the smallest axis-aligned box containing the ROI

BBOX_HEIGHT

Height of the smallest axis-aligned box containing the ROI

BBOX_WIDTH

Width of the smallest axis-aligned box containing the ROI

MAJOR_AXIS_LENGTH

Length (in pixels) of the major axis of the ellipse that has the same normalized second central moments as the region

MINOR_AXIS_LENGTH

Length (in pixels) of the minor axis of the ellipse that has the same normalized second central moments as the region

ECCENTRICITY

Ratio of ROI’s inertia ellipse focal distance over the major axis length

ORIENTATION

Angle between the 0th axis and the major axis of the ellipse that has same second moments as the region

ROUNDNESS

Represents how similar a ROI’s inertia ellipse is to circle. Calculated based on the major and minor exis lengths

EXTENT

Proportion of the pixels (2D) or voxels (3D) in the bounding box that are also in the region. Computed as the area/volume of the object divided by the area/volume of the bounding box

ASPECT_RATIO

The ratio of the major axis to the minor axis of ROI’s inertia ellipse

CONVEX_HULL_AREA

Area of ROI’s convex hull

SOLIDITY

Ratio of pixels in the ROI common with its convex hull image

PERIMETER

Number of pixels in ROI’s contour

EQUIVALENT_DIAMETER

Diameter of a circle with the same area as the ROI

EDGE_MEAN_INTENSITY

Mean intensity of ROI’s contour pixels

EDGE_STDDEV_INTENSITY

Standard deviation of ROI’s contour pixels

EDGE_MAX_INTENSITY

Maximum intensity of ROI’s contour pixels

EDGE_MIN_INTENSITY

Minimum intensity of ROI’s contour pixels

CIRCULARITY

Represents how similar a shape is to circle. Clculated based on ROI’s area and its convex perimeter

EROSIONS_2_VANISH

Number of erosion operations for a ROI to vanish in its axis aligned bounding box

EROSIONS_2_VANISH_COMPLEMENT

Number of erosion operations for a ROI to vanish in its convex hull

FRACT_DIM_BOXCOUNT

Fractal dimension determined by the box counting method according to ISO 9276-6. If C is a fractal set, with fractal dimension DF < D, then the number N of boxes of size R needed to cover the set scales as R^(-DF). DF is known as the Hausdorf dimension, or Kolmogorov capacity, or Kolmogorov dimension, or simply box-counting dimension

FRACT_DIM_PERIMETER

Fractal dimension determined by the perimeter method according to ISO 9276-6. If we approximate ROI’s contour with rulers of length lambda, the perimeter based fractal dimension is the slope of the best fit line of log ROI perimeter versus log lambda, subtracted from 1

WEIGHTED_CENTROID_Y

X-coordinate of centroid

WEIGHTED_CENTROID_X

Y-coordinate of centroid

MIN_FERET_DIAMETER

Feret diameter (or maximum caliber diameter) is the longest distance between any two ROI points along the same (horizontal) direction. This feature is the minimum Feret diameter for angles ranging 0 to 180 degrees

MAX_FERET_DIAMETER

Maximum Feret diameter for angles ranging 0 to 180 degrees

MIN_FERET_ANGLE

Angle of the minimum Feret diameter

MAX_FERET_ANGLE

Angle of the maximum Feret diameter

STAT_FERET_DIAM_MIN

Minimum of Feret diameters of the ROI rotated at angles 0-180 degrees

STAT_FERET_DIAM_MAX

Maximum of Feret diameters of the ROI rotated at angles 0-180 degrees

STAT_FERET_DIAM_MEAN

Mean Feret diameter of the ROI rotated at angles 0-180 degrees

STAT_FERET_DIAM_MEDIAN

Median value of Feret diameters of the ROI rotated at angles 0-180 degrees

STAT_FERET_DIAM_STDDEV

Standard deviation of Feret diameter of the ROI rotated at angles 0-180 degrees

STAT_FERET_DIAM_MODE

Histogram mode of Feret diameters of the ROI rotated at angles 0-180 degrees

STAT_MARTIN_DIAM_MIN

Minimum of Martin diameters of the ROI rotated at angles 0-180 degrees

STAT_MARTIN_DIAM_MAX

Maximum of Martin diameters of the ROI rotated at angles 0-180 degrees

STAT_MARTIN_DIAM_MEAN

Mean of Martin diameter of the ROI rotated at angles 0-180 degrees

STAT_MARTIN_DIAM_MEDIAN

Median value of Martin diameters of the ROI rotated at angles 0-180 degrees

STAT_MARTIN_DIAM_STDDEV

Standard deviation of Martin diameter of the ROI rotated at angles 0-180 degrees

STAT_MARTIN_DIAM_MODE

Histogram mode of Martin diameters of the ROI rotated at angles 0-180 degrees

STAT_NASSENSTEIN_DIAM_MIN

Minimum of Nassenstein diameters of the ROI rotated at angles 0-180 degrees

STAT_NASSENSTEIN_DIAM_MAX

Maximum of Nassenstein diameters of the ROI rotated at angles 0-180 degrees

STAT_NASSENSTEIN_DIAM_MEAN

Mean of Nassenstein diameter of the ROI rotated at angles 0-180 degrees

STAT_NASSENSTEIN_DIAM_MEDIAN

Median value of Nassenstein diameters of the ROI rotated at angles 0-180 degrees

STAT_NASSENSTEIN_DIAM_STDDEV

Standard deviation of Nassenstein diameter of the ROI rotated at angles 0-180 degrees

STAT_NASSENSTEIN_DIAM_MODE

Histogram mode of Nassenstein diameters of the ROI rotated at angles 0-180 degrees

MAXCHORDS_MAX

Maximum of ROI’s longest chords built at angles 0-180 degrees

MAXCHORDS_MAX_ANG

Angle of the chord referenced in MAXCHORDS_MAX

MAXCHORDS_MIN

Minimum of ROI’s longest chords built at angles 0-180 degrees

MAXCHORDS_MIN_ANG

Angle of the chord referenced in MAXCHORDS_MIN

MAXCHORDS_MEDIAN

Median value of ROI’s longest chords built at angles 0-180 degrees

MAXCHORDS_MEAN

Mean value of ROI’s longest chords built at angles 0-180 degrees

MAXCHORDS_MODE

Histogram mode of ROI’s longest chords built at angles 0-180 degrees

MAXCHORDS_STDDEV

Sndard deviation of ROI’s longest chords built at angles 0-180 degrees

ALLCHORDS_MAX

Maximum of all the ROI’s chords built at angles 0-180 degrees

ALLCHORDS_MAX_ANG

Angle of the chord referenced in ALLCHORDS_MAX

ALLCHORDS_MIN

Minimum of all the ROI’s chords built at angles 0-180 degrees

ALLCHORDS_MIN_ANG

Angle of the chord referenced in ALLCHORDS_MIN

ALLCHORDS_MEDIAN

Median value of all the ROI’s chords built at angles 0-180 degrees

ALLCHORDS_MEAN

Mean value of all the ROI’s chords built at angles 0-180 degrees

ALLCHORDS_MODE

Histogram mode of all the ROI’s chords built at angles 0-180 degrees

ALLCHORDS_STDDEV

Sndard deviation of all the ROI’s chords built at angles 0-180 degrees

EULER_NUMBER

Euler characteristic of the ROI - the number of objects in the ROI minus the number of holes assuming the 8-neighbor connectivity of ROI’s pixels

EXTREMA_P1_X

X-ccordinate of ROI’s axis aligned bounding box extremum point #1

EXTREMA_P1_Y

Y-ccordinate of ROI’s axis aligned bounding box extremum point #1

EXTREMA_P2_X

X-ccordinate of ROI’s axis aligned bounding box extremum point #2

EXTREMA_P2_Y

EXTREMA_P3_X

X-ccordinate of ROI’s axis aligned bounding box extremum point #3

EXTREMA_P3_Y

EXTREMA_P4_X

X-ccordinate of ROI’s axis aligned bounding box extremum point #4

EXTREMA_P4_Y

EXTREMA_P5_X

X-ccordinate of ROI’s axis aligned bounding box extremum point #5

EXTREMA_P5_Y

EXTREMA_P6_X

X-ccordinate of ROI’s axis aligned bounding box extremum point #6

EXTREMA_P6_Y

EXTREMA_P7_X

X-ccordinate of ROI’s axis aligned bounding box extremum point #7

EXTREMA_P7_Y

EXTREMA_P8_X

X-ccordinate of ROI’s axis aligned bounding box extremum point #8

EXTREMA_P8_Y

POLYGONALITY_AVE

The score ranges from $ -infty $ to 10. Score 10 indicates the object shape is polygon and score $ -infty $ indicates the ROI shape is not polygon

HEXAGONALITY_AVE

The score ranges from $ -infty $ to 10. Score 10 indicates the object shape is hexagon and score $ -infty $ indicates the ROI shape is not hexagon

HEXAGONALITY_STDDEV

Standard deviation of hexagonality_score relative to its mean

DIAMETER_MIN_ENCLOSING_CIRCLE

Diameter of the minimum enclosing circle

DIAMETER_CIRCUMSCRIBING_CIRCLE

Diameter of the circumscribing circle

DIAMETER_INSCRIBING_CIRCLE

Diameter of inscribing circle

GEODETIC_LENGTH

Geodetic length approximated by a rectangle with the same area and perimeter: $ area = geodeticlength * thickness$; $perimeter = 2 * (geodetic_length + thickness) $

THICKNESS

Thickness approximated by a rectangle with the same area and perimeter: $ area = geodeticlength * thickness$; $perimeter = 2 * (geodetic_length + thickness) $

ROI_RADIUS_MEAN

Mean centroid to edge distance

ROI_RADIUS_MAX

Maximum of centroid to edge distances

ROI_RADIUS_MEDIAN

Median value of centroid to edge distances

Texture features:


Nyxus feature code

Description

GLCM_ASM

GLCM, Angular second moment, IBSI # 8ZQL

GLCM_ACOR

GLCM, Autocorrelation, IBSI # QWB0

GLCM_CLUPROM

GLCM, Cluster prominence, IBSI # AE86

GLCM_CLUSHADE

GLCM, Cluster shade, IBSI # 7NFM

GLCM_CLUTEND

GLCM, Cluster tendency, IBSI # DG8W

GLCM_CONTRAST

GLCM, Contrast, IBSI # ACUI

GLCM_CORRELATION

GLCM, Correlation, IBSI # NI2N

GLCM_DIFAVE

GLCM, Difference average, IBSI # TF7R

GLCM_DIFENTRO

GLCM, Difference entropy, IBSI # NTRS

GLCM_DIFVAR

GLCM, Difference variance, IBSI # D3YU

GLCM_DIS

GLCM, Dissimilarity, IBSI # 8S9J

GLCM_ENERGY

GLCM, Energy

GLCM_ENTROPY

GLCM, Entropy

GLCM_HOM1

GLCM, Homogeneity-1

GLCM_HOM2

GLCM, Homogeneity-2

GLCM_ID

GLCM, Inverse difference, IBSI # IB1Z

GLCM_IDN

GLCM, Inverse difference normalized, IBSI # NDRX

GLCM_IDM

GLCM, Inverse difference moment, IBSI # WF0Z

GLCM_IDMN

GLCM, Inverse difference moment normalized, IBSI # 1QCO

GLCM_INFOMEAS1

GLCM, Information measure of correlation 1, IBSI # R8DG

GLCM_INFOMEAS2

GLCM, Information measure of correlation 2, IBSI # JN9H

GLCM_IV

GLCM, Inverse variance, IBSI # E8JP

GLCM_JAVE

GLCM, Joint average, IBSI # 60VM

GLCM_JE

GLCM, Joint entropy, IBSI # TU9B

GLCM_JMAX

GLCM, Joint maximum (aka max probability), IBSI # GYBY

GLCM_JVAR

GLCM, Joint variance (aka sum of squares), IBSI # UR99

GLCM_SUMAVERAGE

GLCM, Sum average, IBSI # ZGXS

GLCM_SUMENTROPY

GLCM, Sum entropy, IBSI # P6QZ

GLCM_SUMVARIANCE

GLCM, Sum variance, IBSI # OEEB

GLCM_VARIANCE

GLCM, Variance

GLRLM_SRE

Grey level run-length matrix (GLRLM) based feature, Short Run Emphasis

GLRLM_LRE

GLRLM, Long Run Emphasis

GLRLM_GLN

GLRLM, Grey Level Non-Uniformity

GLRLM_GLNN

GLRLM, Grey Level Non-Uniformity Normalized

GLRLM_RLN

GLRLM, Run Length Non-Uniformity

GLRLM_RLNN

GLRLM, Run Length Non-Uniformity Normalized

GLRLM_RP

GLRLM, Run Percentage

GLRLM_GLV

GLRLM, Grey Level Variance

GLRLM_RV

GLRLM, Run Variance

GLRLM_RE

GLRLM, Run Entropy

GLRLM_LGLRE

GLRLM, Low Grey Level Run Emphasis

GLRLM_HGLRE

GLRLM, High Grey Level Run Emphasis

GLRLM_SRLGLE

GLRLM, Short Run Low Grey Level Emphasis

GLRLM_SRHGLE

GLRLM, Short Run High Grey Level Emphasis

GLRLM_LRLGLE

GLRLM, Long Run Low Grey Level Emphasis

GLRLM_LRHGLE

GLRLM, Long Run High Grey Level Emphasis

GLDZM_SDE

GLDZM, Small Distance Emphasis

GLDZM_LDE

GLDZM, Large Distance Emphasis

GLDZM_LGLE

GLDZM, Low Grey Level Emphasis

GLDZM_HGLE

GLDZM, High GreyLevel Emphasis

GLDZM_SDLGLE

GLDZM, Small Distance Low Grey Level Emphasis

GLDZM_SDHGLE

GLDZM, Small Distance High GreyLevel Emphasis

GLDZM_LDLGLE

GLDZM, Large Distance Low Grey Level Emphasis

GLDZM_LDHGLE

GLDZM, Large Distance High Grey Level Emphasis

GLDZM_GLNU

GLDZM, Grey Level Non Uniformity

GLDZM_GLNUN

GLDZM, Grey Level Non Uniformity Normalized

GLDZM_ZDNU

GLDZM, Zone Distance Non Uniformity

GLDZM_ZDNUN

GLDZM, Zone Distance Non Uniformity Normalized

GLDZM_ZP

GLDZM, Zone Percentage

GLDZM_GLM

GLDZM, Grey Level Mean

GLDZM_GLV

GLDZM, Grey Level Variance

GLDZM_ZDM

GLDZM, Zone Distance Mean

GLDZM_ZDV

GLDZM, Zone Distance Variance

GLDZM_ZDE

GLDZM, Zone Distance Entropy

GLSZM_SAE

GLDZM, Grey level size zone matrix (GLSZM) based feature, Small Area Emphasis

GLSZM_LAE

Large Area Emphasis

GLSZM_GLN

Grey Level Non - Uniformity

GLSZM_GLNN

Grey Level Non - Uniformity Normalized

GLSZM_SZN

Size - Zone Non - Uniformity

GLSZM_SZNN

Size - Zone Non - Uniformity Normalized

GLSZM_ZP

Zone Percentage

GLSZM_GLV

Grey Level Variance

GLSZM_ZV

Zone Variance

GLSZM_ZE

Zone Entropy

GLSZM_LGLZE

Low Grey Level Zone Emphasis

GLSZM_HGLZE

High Grey Level Zone Emphasis

GLSZM_SALGLE

Small Area Low Grey Level Emphasis

GLSZM_SAHGLE

Small Area High Grey Level Emphasis

GLSZM_LALGLE

Large Area Low Grey Level Emphasis

GLSZM_LAHGLE

Large Area High Grey Level Emphasis

GLDM_SDE

Grey level dependency matrix (GLDM) based feature, Small Dependence Emphasis(SDE)

GLDM_LDE

Large Dependence Emphasis (LDE)

GLDM_GLN

Grey Level Non-Uniformity (GLN)

GLDM_DN

Dependence Non-Uniformity (DN)

GLDM_DNN

Dependence Non-Uniformity Normalized (DNN)

GLDM_GLV

Grey Level Variance (GLV)

GLDM_DV

Dependence Variance (DV)

GLDM_DE

Dependence Entropy (DE)

GLDM_LGLE

Low Grey Level Emphasis (LGLE)

GLDM_HGLE

High Grey Level Emphasis (HGLE)

GLDM_SDLGLE

Small Dependence Low Grey Level Emphasis (SDLGLE)

GLDM_SDHGLE

Small Dependence High Grey Level Emphasis (SDHGLE)

GLDM_LDLGLE

Large Dependence Low Grey Level Emphasis (LDLGLE)

GLDM_LDHGLE

Large Dependence High Grey Level Emphasis (LDHGLE)

NGLDM_LDE

Low Dependence Emphasis

NGLDM_HDE

High Dependence Emphasis

NGLDM_LGLCE

Low Grey Level Count Emphasis

NGLDM_HGLCE

High Grey Level Count Emphasis

NGLDM_LDLGLE

Low Dependence Low Grey Level Emphasis

NGLDM_LDHGLE

Low Dependence High Grey Level Emphasis

NGLDM_HDLGLE

High Dependence Low Grey Level Emphasis

NGLDM_HDHGLE

High Dependence High Grey Level Emphasis

NGLDM_GLNU

Grey Level Non-Uniformity

NGLDM_GLNUN

Grey Level Non-Uniformity Normalised

NGLDM_DCNU

Dependence Count Non-Uniformity

NGLDM_DCNUN

Dependence Count Non-Uniformity Normalised

NGLDM_GLM

Grey Level Mean

NGLDM_GLV

Grey Level Variance

NGLDM_DCM

Dependence Count Mean

NGLDM_DCV

Dependence Count Variance

NGLDM_DCE

Dependence Count Entropy

NGLDM_DCENE

Dependence Count Energy

NGTDM_COARSENESS

Neighbouring Grey Tone Difference Matrix (NGTDM) Features, Coarseness

NGTDM_CONTRAST

NGTDM, Contrast

NGTDM_BUSYNESS

NGTDM, Busyness

NGTDM_COMPLEXITY

NGTDM, Complexity

NGTDM_STRENGTH

NGTDM, Strength

Radial intensity distribution features:


Nyxus feature code

Description

ZERNIKE2D

Zernike features

FRAC_AT_D

Fraction of total intensity at a given radius

MEAN_FRAC

Mean fractional intensity at a given radius

RADIAL_CV

Coefficient of variation of intensity within a ring (band), calculated across $n$ slices

Frequency and orientational features:


Nyxus feature code

Description

GABOR

A set of Gabor filters of varying frequencies and orientations

2D image moments:


Nyxus feature code

Description

SPAT_MOMENT_00

Spatial (raw) moments

SPAT_MOMENT_01

of order 00, 01, 02, etc

SPAT_MOMENT_02

SPAT_MOMENT_03

SPAT_MOMENT_10

SPAT_MOMENT_11

SPAT_MOMENT_12

SPAT_MOMENT_20

SPAT_MOMENT_21

SPAT_MOMENT_30

WEIGHTED_SPAT_MOMENT_00

Spatial moments weighted by pixel distance to ROI edge

WEIGHTED_SPAT_MOMENT_01

WEIGHTED_SPAT_MOMENT_02

WEIGHTED_SPAT_MOMENT_03

WEIGHTED_SPAT_MOMENT_10

WEIGHTED_SPAT_MOMENT_11

WEIGHTED_SPAT_MOMENT_12

WEIGHTED_SPAT_MOMENT_20

WEIGHTED_SPAT_MOMENT_21

WEIGHTED_SPAT_MOMENT_30

CENTRAL_MOMENT_02

Central moments

CENTRAL_MOMENT_03

CENTRAL_MOMENT_11

CENTRAL_MOMENT_12

CENTRAL_MOMENT_20

CENTRAL_MOMENT_21

CENTRAL_MOMENT_30

WEIGHTED_CENTRAL_MOMENT_02

Central moments weighted by pixel distance to ROI edge

WEIGHTED_CENTRAL_MOMENT_03

WEIGHTED_CENTRAL_MOMENT_11

WEIGHTED_CENTRAL_MOMENT_12

WEIGHTED_CENTRAL_MOMENT_20

WEIGHTED_CENTRAL_MOMENT_21

WEIGHTED_CENTRAL_MOMENT_30

NORM_CENTRAL_MOMENT_02

Normalized central moments

NORM_CENTRAL_MOMENT_03

NORM_CENTRAL_MOMENT_11

NORM_CENTRAL_MOMENT_12

NORM_CENTRAL_MOMENT_20

NORM_CENTRAL_MOMENT_21

NORM_CENTRAL_MOMENT_30

NORM_SPAT_MOMENT_00

Normalized (standardized) spatial moments

NORM_SPAT_MOMENT_01

NORM_SPAT_MOMENT_02

NORM_SPAT_MOMENT_03

NORM_SPAT_MOMENT_10

NORM_SPAT_MOMENT_20

NORM_SPAT_MOMENT_30

HU_M1

Hu’s moment 1

HU_M2

Hu’s moment 2

HU_M3

Hu’s moment 3

HU_M4

Hu’s moment 4

HU_M5

Hu’s moment 5

HU_M6

Hu’s moment 6

HU_M7

Hu’s moment 7

WEIGHTED_HU_M1

Weighted Hu’s moment 1

WEIGHTED_HU_M2

Weighted Hu’s moment 2

WEIGHTED_HU_M3

Weighted Hu’s moment 3

WEIGHTED_HU_M4

Weighted Hu’s moment 4

WEIGHTED_HU_M5

Weighted Hu’s moment 5

WEIGHTED_HU_M6

Weighted Hu’s moment 6

WEIGHTED_HU_M7

Weighted Hu’s moment 7

Neighbor features:


Nyxus feature code

Description

NUM_NEIGHBORS

The number of neighbors bordering the ROI’s perimeter within proximity radius specified by command line argument –pixelDistance. (Default value of –pixelDistance is 5.) Algorithmically calculating this feature invilves solving the nearest neighbors search problem that in turn involves the proximity measure and the proximity threshold. Particularly, this plugin uses the \(L_2\) norm measure over Cartesian space of pixel coordinates and parameter –pixelDistance

PERCENT_TOUCHING

Percent of ROI’s contour pixels located at distance 0 from neighboring other ROIs’s contour

CLOSEST_NEIGHBOR1_DIST

Distance in pixels from ROI’s centroid to the nearest neighboring ROI’s centroid

CLOSEST_NEIGHBOR1_ANG

Angle in degrees between ROI’s centroid and its nearest neighboring ROI’s centroid

CLOSEST_NEIGHBOR2_DIST

Distance in pixels from ROI’s centroid to the second nearest neighboring ROI’s centroid

CLOSEST_NEIGHBOR2_ANG

Angle in degrees between ROI’s centroid and its second nearest neighboring ROI’s centroid

ANG_BW_NEIGHBORS_MEAN

Mean angle in degrees between ROI’s centroid and centroids of its neighboring ROIs

ANG_BW_NEIGHBORS_STDDEV

Standard deviation in degrees of angles between ROI’s centroid and centroids of its neighboring ROIs

ANG_BW_NEIGHBORS_MODE

Mode value in degrees of angles between ROI’s centroid and centroids of its neighboring ROIs